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Geregistreerd op: 08 Dec 2017 Berichten: 1092
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Geplaatst: 17-04-2018 10:53:15
Onderwerp: Rayshawn-Jenkins-
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WASHINGTON Rayshawn Jenkins Chargers Jersey , Oct. 16 (Xinhua) -- Canadian researchers said Wednesday they have developed an antibody treatment that may be able to prevent death from Ebola virus even when given three full days after infection.
The findings, published in the U.S. journal Science Translational Medicine, suggested that it may be possible to develop a cure for Ebola even after the virus can be detected in the blood and disease symptoms have become apparent.
Although rare, Ebola virus is considered one of the most if not the most aggressive virus known to date in part because of its rapidity to kill, which can be within one week from exposure or three to four days from when the first symptoms become apparent. This leaves very little time for any treatment to act and save a sick individual.
"For this reason, such a treatment has been considered by many to be closer to the domain of science fiction than contemporary scientific research," lead author Qiu Xiangguo at the Public Health Agency of Canada told Xinhua.
In their study, the researchers gave Ebola-infected monkeys a treatment made of three specific antibodies in combination with interferon alpha, a molecule that is produced naturally by the body to fight viruses.
The antibodies are "like three little but powerful missiles" that target three different outer regions of the virus, Qiu said. Once in contact with the virus external coat, these antibodies interfere with the virus lifecycle and reduce the ability of the virus to reproduce. At the same time, the interferon alpha boosts the defenses of the infected individual by stimulating a natural but rapid and robust anti-viral response, she said.
The combination of antibody and interferon therapy was 75 percent and 100 percent protective in cynomolgus and rhesus monkeys when given three days post-infection. About half of the cynomolgus monkeys were protected at four days post-infection in cases where only interferon alpha was given earlier, one day post- infection, Qiu said.
"Although we were very optimistic we were not expecting to see 100 percent survival in Ebola-infected non-human primates when treated only three days before they succumb to the disease on average," Qiu said.
"This study shows that what seemed impossible to many, i.e. to develop a cure capable of stopping Ebola virus on its track only a few days before death, has now been made and proven efficacious in conditions that are at least as serious if not more severe than what has been observed and described in humans," she added.
The researchers said they have tentatively scheduled a phase I safety trial, slated for the end of 2014 or early 2015, to test the combination therapy in humans.
Dragon boating is an ancient sport that originated in china in about 500 B.C. Chinese people played the sport in festivals and believed that it brings luck while celebrating for the planning of summer rice crop. The dragon boat got its name from the popular shape of the boat. The boat itself was a long craft designed somewhat like a canoe. During racing events, boats were decorated with heads and tails of the dragon, and body of the boat was painted in red, gold and other colors as part of Chinese tradition.
The crew of the boat consisted of twenty paddlers, one drummer, and one steersman. Paddlers sit in the middle of the boat and each rider carries a large paddle for rowing. Drummer sit in front of the boat facing towards the paddlers and steersman sat at boat end to steer the boat or give direction with a long paddle.
Although the sport originated in china, today it is played all over the world. The first international Hong Kong dragon boat races took place in 1976, after which International Dragon Boat federation(IDBF) was formed in 1991. By looking this federation, European Dragon Boat Federation(EDBF) and Asian Dragon Boat federation (ADBF) were formed and are now governing dragon boat races in 60 countries.
Two kinds of races, sports races, and festival races are held today. Sports races usually have strict rules and are held at distances of 200, 500, 1000 meters, whereas festival races are informal and are held up to a distance of 500 meters.
Dragon boating is the fastest growing watersport where thousands of new people participate every year. It also has clubs and organizations spanning 60 countries. Its not just a water sport, but also a great outdoor activity means to get exercises and meet people.
With the formation of clubs and organizations for dragon boating, more people are participating in dragon boat events worldwide. Such clubs and organizations not only conduct dragon boat events but also give training in the water sport to their club members. Participants need to register themselves with a dragon boat club and buy dragon boat paddles to enjoy the water sport. A life jacket is provided to each participant and dragon boats are provided to each group by such clubs.
Dragon boating is a wet sport, thus participants need to wear comfortable clothing (shorts, Ύ pants), shoes, sunglasses before playing the watersport. They can even buy dragon boat accessories like dragon boat paddle bag, paddle blade cover, and a leg cell phone case to protect their boat paddles and cell phones.
Today, dragon boat paddles are available in various customized designs and colors. This allows customers to choose a boat paddle of their choice. Thus Sports paddle manufacturers are providing boat paddles of various designs and colors at an affordable price to their customers. They provide boat paddles that are made up of carbon fibers. These paddles even have T-grip at the end of the paddles which provide a good grip to paddlers. For more information on such Dragon boat paddles and accessories, you can log on to Hornetwatersports.
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